Pre-implantation Genetic Diagnosis (PGD)

Pre-implantation Genetic Diagnosis (PGD)

Pre-implantation genetic diagnosis (PGD) is a diagnostic procedure involving checking the genes and chromosomes of embryos created through assisted reproductive technologies. It helps couples who might have an inheritable condition to avoid passing it to their babies.

PGD may be recommended by specialists when patients have had a child with a serious genetic condition, or when they have a family history of genetic or chromosomal problems, if the maternal age is higher (40 years), or when they have ended previous pregnancies because of a genetic condition.

The procedure for PGD normally involves the following steps:

  1. Patients undergo IVF treatment to collect and fertilize the eggs
  2. Embryo is grown in the laboratory for 48 to 72 hours
  3. The embryologist removes a cell or two cells from the embryo
  4. These cells are tested to see if the embryo contains the gene that causes the genetic condition in the family
  5. The healthy embryo, unaffected by the condition, is transferred to the womb to allow it to develop
  6. Other genetically unaffected embryos can be frozen

The risk associated with PGD is that there is a possibility of some embryos being damaged by the process of cell removal and that some tests may not be completely conclusive.

It is currently difficult to assess the success rates for PGD because of sparse data available. Most couples use PGD because they do not want to bear a child with a genetic disease.

This is a brief overview of PGD. If you have any further queries, please reach us at  or to schedule an appointment with one of our doctors, click here. We would be happy to be of assistance.

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